Wednesday, February 18, 2015

Finding Serious Case Reviews

Last year, in response to an enquiry, I put together a handout for social work students at the University of Leicester about how to find Serious Case Reviews.  I have revised the text for this posting, and made the revised handout available to students via the "My Subject" page for Social Work. I checked the links on 5th August 2015.

What is a Serious Case Review (SCR)?

In England, Local Safeguarding Children Boards (LSCB) conduct a review of any “serious case”.  A case is a “serious case” if abuse or neglect of a child is known or suspected, and if a child has died or been seriously harmed and where there is concern about how agencies have worked together to safeguard that child.  SCRs are conducted in accordance with guidance published as chapter 4 of the 2013 publication Working together to safeguard children.

The Serious Case Review Panel is a national panel of independent experts who advise LCSBs about conducting and publishing SCRs. 

The NSPCC have information about Serious Case Reviews. In Scotland, Wales and Northern Ireland, there are different arrangements, and the NSPCC has information (scroll down). 

Publication of SCRs

The guidance states, in relation to publication of reports:


“All reviews of cases meeting the SCR criteria should result in a report which is published and readily accessible on the LSCB’s website for a minimum of 12 months. Thereafter the report should be made available on request.”   
(Working together to safeguard children, p. 71)
This suggests that SCRs are easy to find.  However, LSCBs must consider, when publishing SCRs, how to manage the impact of the report on the child and the family, and must comply with the Data Protection Act and any court orders.  They must also send the report to the national panel of independent experts one week before publication, so that the panel can advise if the report should not be published.   

In my (limited) experience, reviews seem to be available only in edited or redacted form, or only as summaries.  This is perhaps explained by the presence of court orders or legal proceedings, of data protection issues, or of guidance from the national panel.


Finding SCRs


Names of subjects

Legal and other issues may mean that names of children and families are removed.  This may make it difficult to find a specific report.  If you cannot find it by name of child, try searching by name of place.

NSPCC Library Catalogue
LCSBs are asked to submit published reports to the NSPCC for inclusion in a national repository of SCRs, which was set up in late 2013.  The repository forms part of the NSPCC’s Library catalogue.  There is a link to the National Case Review Repository here, and links to reviews published in 2014 and 2015 (scroll down).   
 


Social Care Online
Some SCRs are indexed in Social Care Online.    Doing an Advanced search for the subject term serious case reviews seems to find many, and searching for relevant search terms will find particular ones.


LSCB websites
Otherwise you should be able to locate a report via the website of the LSCB in question.  You can find the LSCB website by following links from the appropriate local authority or by a web search.

Sunday, February 15, 2015

Research funding and conflicts of interest

The Guardian reports Susan Jebb's response to a BMJ piece about the food industry funding research into food and nutrition topics.  Professor Jebb is chair of the Public Health Responsibility Deal, and the Guardian reports several people who defend her independence, which she herself asserts.   The three articles referenced in the BMJ piece appear to be peer reviewed articles.  The ICMJE Conflicts of Interest form (found via the EQUATOR site) indicates that authors need to declare any associations with entities relevant to the work.  Do peer reviewers need to take this into account?   Nothing I have found indicates they have to.  Do they in fact know who funded the research they are reviewing?   Would it give them information that might help them identify who wrote the research?   They do of course have to critique the methodologies used.   If the funders had any influence over the research, would it show up in the choice of methodology, the presentation of results, or the discussion of those results.  Interestingly, Behind the Headlines and CASP checklists both appear to make no reference to who funded the research being critiqued.

The World Association of Medical Editors have a document about conflict of interests, which describes what authors, editors and reviewers have to do, but reviewers' COI seems to relate to conflicts of interest with the authors, or their field of research, rather than whether they shoudl know or take into account the authors' COI regarding sources of funding.  

EQUATOR has guidance on industry sponsored research, largely about using industry "ghost" writers to produce the papers, but it does include links to guidance for pharmaceutical companies.

Another Guardian piece reports that research into plain cigarette packaging in Australia, which was publicised by the tobacco industry as showing no effect, and which was funded by a tobacco company, has been criticised "on the BMJ website".  Actually, the piece concerned is not on the BMJ website but a peer reviewed article published online in the journal Tobacco Control (which is a BMJ journal).

This research was not peer reviewed.  I (along with at least one commenter on the Guardian site) wondered why not. But, looking for the paper online reveals it is a working paper, published by the Department of Economics at the University of Zurich.  My limited understanding (I am a medical librarian, really!) of economics literature is that "working papers" are an important way to publish research in economics, and are discussion papers, preliminary results, not peer reviewed before publication.  Rather, they are  in effect peer reviewed after publication.

So, the Tobacco Control article is perhaps part of that post publication review.  The Guardian link to it, but you will need to pay or have a subscription to read the full article.   The University of Leicester has a subscription, so I have seen the full thing.   The Tobacco Control paper authors say that the Zurich authors were provided with the data (from an Australian market research company) by the tobacco company in question, which I can't immediately see in their working paper, but their arguments seem really to be with the statistical methods employed by the Zurich authors.  That would perhaps have been picked up by peer reviewers, but is now being picked up by this post publication review of a working paper.

Perhaps accepting funding will restrict the places where you can publish (Tobacco Control, for example, will not accept work funded by the tobacco industry).  I do think that research funders should not be able to influence what the researchers find or report.  That should be made clear to them when the funding is accepted and presumably is the sort of thing that your institution would advise you about when considering whether to accept funding or not.  

However, there is a Cochrane Review (Lundh A, Sismondo S, Lexchin J, Busuioc OA, Bero L. Industry sponsorship and research outcome. Cochrane Database of Systematic Reviews 2012, Issue 12. Art. No.: MR000033. DOI: 10.1002/14651858.MR000033.pub2), which suggests that industry sponsorship does in fact influence results.

More research needed on my part, perhaps. 

Karl Bonhoeffer

Many years ago I read a lot about Dietrich Bonhoeffer, the minister and theologian.  His ideas about the church and Christianity I found interesting, and I was also interested in his involvement in plots to kill Hitler.  He was executed in 1945 for that involvement.  

And so I discovered that his father, Karl (1868-1948) was a psychiatrist.  And because at the time I worked at the Royal Society of Medicine Library in London, which was (and is) a research library of historical record which kept all sorts of things, and we had Index Medicus in print and Medline on CD Rom, I could find material about him and then find the actual articles.  

Karl seemed to have been a psychiatrist of some note.   People published Festschriften in his honour when he reached significant ages (and we had them, in German).  But what did he know about what his family were doing?   Two sons and two sons in law were executed by the Nazis.   I seem to remember reading in one biography of Dietrich that Dietrich had used Karl's car to transport material to use in an attempt on Hitler's life.    And what did he think of the Nazis' policy of sterilisation?   Was he involved?  I seem to remember material that indicated he was.  But why?  


I had at the time written an article about Jean-Paul Marat, the French revolutionary, who was a doctor, and meant to write something about Karl Bonhoeffer.  But other things happened instead, and I never did.  Perhaps this is it!   

Anyway, I have just looked again for material about Karl, using the University of Leicester Library search, and found a new thing, and a thing I am not sure I have found before.  

The new thing comes from a symposium about Karl's role in Nazism, and is an article by Hanfried Helmchen published in German this year in Der Nervenarzt, and asking about his position on sterilisation (1).   And a short piece in the American Journal of Psychiatry in 1944 (2), which seems to be a reprint of a Lancet obituary, reporting that Karl had died the previous year at the age of 75.   In fact, he did not die until 1948, which leaves me wondering where that report came from and why.

I hope this is a work in progress!

References

(1) Helmchen H. Bonhoeffers Position zur Sterilisation psychisch Kranker. Nervenarzt 2015;86:77-84.  doi: 10.1007/s00115-013-3999-x
 
(2)  Karl Bonhoeffer. Am J Psychiatr 1944;101:127-8.



Wednesday, February 11, 2015

Searching PROSPERO

Prospero is an international database of systematic reviews.  Reviewers can register review protocols in it, and link to publications once they appear.   Prospero is hosted by the Centre for Reviews and Dissemination at the University of York.  There is information about registration and the data that is required here.

Searching Prospero before you start a review could stop you duplicating work that is already in progress.  

As part of an enquiry at work, I was searching Prospero for reviews to include in a review of reviews (an "umbrella review").   Searching Prospero would locate reviews in progress, and would identify published reviews (alongside those identified using Medline and other databases). 

I have not found any search help specific to Prospero.  I am fairly sure the search help at http://www.crd.york.ac.uk/crdweb/GuideToSearching.asp applies to the other CRD databases.  

The References and Resources section contains a lot of useful information, including reviews of progress, and there are some interesting articles about Prospero under "Registering a systematic review", but the main emphasis of all the material seems to be about registration, not searching.  So, I thought it might be useful to "publish" my notes about searching Prospero.



Complex search strategies are difficult.  You can't see a search history, and so can only submit one query at a time.  If you use one search box, you can't use Boolean operators, although you can use * to truncate.  You can't enter phrases in inverted commas, but I wonder if phrase searching is the default.  Using more than one search box does give you a way to search using Boolean in one field (change the drop down box at the top) or across fields, but you have to have just AND or OR.  
You can't export results, only view them, so reviewing results for items to include in your research would need to be done on screen, and I am not sure how you would then put those items into reference management software for retention.

The Participants/Population field records details about the group(s) being studied in the review.  My enquiry involved finding material relating to older people.  Searching for aged did not work, as this found phrases like "patients aged 10 or above".  Older worked better, although that still found phrases like "30 years and older".  Elderly and geriatric worked as well.  There is no standardisation in this field, and no equivalent of Medline's age limits.

You can display all published records, and doing so shows that at the moment there are 5739 records, so the dataset is a lot smaller than something like Medline, and this combined with the fact that searching Prospero would be to augment more systematic searches done elsewhere, means that broader searches are still practical.