Is evidence based medicine relevant to the developing world?

Is the subject of a paper in PLoS Medicine, which argues that systematic reviews have yet to achieve their potential as a resource for practitioners in the developing world. This is because they concentrate on conditions and diseases prevalent in the more developed world, and tend to exclude studies from the less developed world. If the condition studied is relevant, it could be that the interventions discussed are not appropriate or affordable. The reasons for these things are looked at, and some solutions are discussed.