Tuesday, April 26, 2022

Hepatitis of unknown aetiology

The BBC and STAT are both reporting today (26th July 2022) two unpublished studies that may offer new evidence on the cause of this hepatitis.  I think one is this, in medrxiv.  


Since the 1st January there have been 263 cases of acute hepatitis in children (figure from UKHSA news page linked below, last updated 7th July 2022), where the "usual" A - E hepatitis viruses have not been detected.

The cases are predominantly in children under 5.

The UKHSA has issued a Technical Briefing, and there is also a news page linking to that and with more information, including a list of hepatitis symptoms.

There is mention on the NHS (UK) page about hepatitis, which also gives information about symptoms.

There is a BMJ news item, with some rapid responses.   There is a news analysis (from 26th April) as well.

NEW - ECDC news item

The Lancet has a global report (a subscription or library access may be needed to read this)


There are cases in other countries as well and the WHO has a disease outbreak news item.  

So does the BBC, which reports that the UKHSA thinks adenovirus F41 may be a cause - the technical briefing does mention that this has been detected in a number of people and the BBC items quotes someone from the UKHSA.


STAT reports CDC investigations, and the report, dated 6th May 2022, also reports UKHSA investigations.

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